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The FDA alerted healthcare professionals and patients that its reviewing new safety findings that report liver-related adverse events in patients taking the medication known as orlistat. Orlistat has been widely sold in the United States as the prescription medicine, Xenical. It can be found over the counter as a supplement called Alli as a fat loss supplement.

From the years of 1999 through 2008, there have been 32 various reports of serious liver injury, including liver failure, in patients using Orlistat have been submitted to FDA’s Adverse Event Reporting System. The main symptoms that have been reported were jaundice, weakness, and abdominal pain.

The FDA has not yet advised healthcare professionals to change their prescribing practices with Orlistat. Surprisingly, the FDA has not even recommended consumers currently taking Xenical to stop taking it as prescribed, or even suggest that those using over-the-counter Alli to stop using it as directed.

Shapiro, Cooper Lewis & Appleton personal injury law firm is based in Virginia (VA), with an office also in Elizabeth City, in Northeast North Carolina (NC), practicing primarily in the southeastern U.S. and handles only injury law, including car, truck, railroad, and medical negligence cases and more. Our Carolina injur law website is:, the firm edits the injury law blogs Virginia Beach Injuryboard, Norfolk Injuryboard, as well as the Northeast North Carolina Injuryboard and also hosts a YouTube injury law video library covering many FAQ’s on personal injury subjects. Lawyers licensed in: VA, NC, SC, WV, DC, KY.


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